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Med. interna (Caracas) ; 33(2): 72-83, 2017. ilus, tab
Article in Spanish | LIVECS, LILACS | ID: biblio-1009158

ABSTRACT

El síndrome antifosfolípido está definido por la combinación de manifestaciones clínicas trombóticas y/u obstétricas y un título persistentemente alto y significativo de anticuerpos antifosfolípidos. La presencia de múltiples trombos en lechos vasculares pequeños que lleva a falla multiorgánica, simultáneamente o en menos de 1 semana, define al síndrome antifosfolípido catastrófico el cual conlleva alta mortalidad; sin embargo, la sospecha diagnóstica y la institución temprana del tratamiento, definitivamente inciden en el pronóstico de éstos pacientes(AU)


Antiphospholipid syndrome is defined by the combination of thrombotic and/or obstetric clinical manifestations and a persistently high and significant title of antiphospholipid antibodies. The presence of multiple thrombi in small vascular beds leading to multi-organ failure that occurs simultaneously or in less than 1 week, and defines the catastrophic antiphospholipid syndrome which carries high mortality, The suspected diagnosis and early treatment affects the prognosis of these patients(AU)


Subject(s)
Humans , Male , Female , Heparin/administration & dosage , Antiphospholipid Syndrome/complications , Antibodies, Antiphospholipid/chemistry , Venous Thrombosis/etiology , Cardiovascular Diseases , Internal Medicine
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